Received: 15 December 2021
Accepted: 4 April 2022
First Online: 21 April 2022
: This study had been approved by institutional review board of Fuwai hospital, Peking union medical college and Chinese academy of medical sciences. All methods were performed in accordance with the relevant guidelines and regulations. The written informed consents were obtained from all participants. The permission to access and use the raw data was granted by Prof. Shengshou Hu and from the Fuwai hospital.
: Not applicable.
: The authors declare that they have no competing interests.