Funding for this research was provided by:
National Institute for Health Research (HTA, HTA, HTA, HTA, HTA)
Received: 11 September 2021
Accepted: 16 May 2022
First Online: 6 June 2022
: The study (pilot and main trial) was performed in accordance with the Declaration of Helskini and was approved by the London-Queen Square Research Ethics Committee, reference 17/LO/0095. Informed consent was obtained from all study participants.
: Consent for publication was received from all participants before their commencement in the study.
: SJCT is the chief investigator or co-investigator on multiple previous and current research grants from the UK National Institute for Health Research and CRC UK. All authors declare that they have no competing interests.