Funding for this research was provided by:
Received: 13 April 2017
Accepted: 10 November 2017
First Online: 20 December 2017
Ethics approval and consent to participate
: All participants will give written informed consent. The study protocol was reviewed and approved by the medical research ethics committee of the MC Slotervaart / Reade (number P1661), and authorized by the competent authority in accordance with the Dutch Medical Research Involving Human Subjects Act (WMO).
: Not applicable.
: Zambon BV the Netherlands provided research support by providing the study medication for this trial. The authors declare that they have no further competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.