Funding for this research was provided by:
Nature Science Foundation of China (NSFC 81871967)
Social Development Foundation of Jiangsu Province of China (No.BE2018604)
Jiangsu Provincial Medical Talent, and the Nanjing Science and Technology Project (No.201803028)
Received: 1 August 2019
Accepted: 31 October 2019
First Online: 21 November 2019
Ethics approval and consent to participate
: This study was approved by Ethic Committee of Nanjing Drum Tower Hospital, and this Ethic Committee comply with the Declaration of Helsinki (Approval No. 2018–085-01). And informed consent was obtained from all individual participants included in the study.
: Not applicable. Our manuscript does not contains any individual person’s data in any form (including individual details, images or videos).
: The authors declare that they have no competing interests.