Funding for this research was provided by:
Bundesministerium für Bildung und Forschung (01GL1703A)
Received: 10 January 2019
Accepted: 25 February 2019
First Online: 4 March 2019
Ethics approval and consent to participate
: Ethical approval for the study was granted by the internal review board at the Medical Faculty of the University of Freiburg, Germany (no. 495–17, date: 19th December 2017). Written informed consent will be requested from subjects or their legal representatives before enrolment. If a patient has a legal guardian, proxy consent is used. In Germany having a legal guardian is determined within a formal legal process. If a patient has a legal guardian, this is recorded within the patient file. If a legal guardian is pre-sent, the legal guardian decides and specifies patients assent.
: Not applicable.
: The authors declare that they have no competing interests.
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