Saito, Hiroshi
Matsue, Yuya
Kamiya, Kentaro
Kagiyama, Nobuyuki
Maeda, Daichi
Endo, Yoshiko
Ueno, Hidenao
Yoshioka, Kenji
Mizukami, Akira
Saito, Kazuya
Ogasahara, Yuki
Maekawa, Emi
Konishi, Masaaki
Kitai, Takeshi
Iwata, Kentaro
Jujo, Kentaro
Wada, Hiroshi
Hiki, Masaru
Dotare, Taishi
Sunayama, Tsutomu
Kasai, Takatoshi
Nagamatsu, Hirofumi
Ozawa, Tetsuya
Izawa, Katsuya
Yamamoto, Shuhei
Aizawa, Naoki
Wakaume, Kazuki
Oka, Kazuhiro
Momomura, Shin-ichi
Minamino, Tohru
Funding for this research was provided by:
Japan Society for the Promotion of Science (18K15862)
Japan Heart Foundation Research Grant
Novartis Pharma Research Grants
Article History
Received: 3 July 2021
Accepted: 16 May 2022
First Online: 5 July 2022
Declarations
:
: All participants were notified regarding their participation in the study, and it was explained that they were free to opt-out of participation at any time. The study was conducted in compliance with the principles of the Declaration of Helsinki and Japanese Ethical Guidelines for Medical and Health Research involving Human Subjects. Since this was an observational study without invasive procedures or interventions, written informed consent was not required under the Ethical Guidelines for Medical and Health Research Involving Human Subjects, issued by the Japanese Ministry of Health, Labor, and Welfare. The study protocol was approved by the ethics committee of each participating hospital. Study information (including the objectives, inclusion and exclusion criteria, primary outcome, and names of participating hospitals) was published in the University Hospital Medical Information Network (UMIN-CTR, unique identifier: UMIN000023929) before the first patient was enrolled. The data used in this study were anonymized before its use.
: Consent for publication was obtained from all participants in this study using an opt-out option.
: YM and TK are affiliated with a department endowed by Philips Respironics, ResMed, Teijin Home Healthcare, and Fukuda Denshi. YM received an honorarium from Otsuka Pharmaceutical Co. and Novartis Japan. NK reports grants from Philips, grants from Asahi KASEI Corporation, Toho Holdings Co. Ltd., and Inter Reha Co. Ltd. outside the submitted work. KK received research funding from Eiken Chemical Co., Ltd. Other authors have nothing to declare.