Funding for this research was provided by:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (MCT/CNPq/MS-SCTIE-DECIT N25/2006)
National Institutes of Health on the ICOHRTA (5 U2RTW006883-02)
Received: 28 August 2016
Accepted: 17 January 2018
First Online: 8 February 2018
Ethics approval and consent to participate
: Sputum culturing of individuals suspected to have TB is done routinely at clinics in the Vitória metropolitan area and the TB Reference Laboratory located at the Infectious Diseases Laboratory of the Federal University of Espirito Santo (UFES). The Mtb isolates are routinely stored by this laboratory for use in outbreak investigations and epidemiologic surveillance. This study was a retrospective analysis of data collected routinely during activities of the state TB control program. Patients were not contacted to request additional information. The study was reviewed and approved by the institutional review board of Universidade Federal do Espírito Santo (UFES; under number 121/06) who granted permission for use of the Mtb isolates and clinical data for the purposes of the study and waived the need for written informed consent from participants as the study involved no more than minimal risk and was done with existing microbiology specimens. Patients had an identification number for clinical purposes while cultures had a different accession number for laboratory purposes. To protect patient confidentiality, only one investigator (ELM) had access to both de-identification codes and was the person that linked of the clinical and culture databases for this study. After linkage, a new code number was created for each record for use in the study analysis.
: Not applicable
: The author(s) declare that they have no competing interests.
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