Funding for this research was provided by:
National Key Technologies R&D Program for the 13th Five-year Plan (2017ZX10202101)
Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2017-12M-1-014)
Received: 23 June 2019
Accepted: 9 January 2020
First Online: 21 January 2020
Ethics approval and consent to participate
: The two parent trials were approved by the Institutional Review Board of the Peking Union Medical College Hospital, Beijing, China, prior to initiation of study activities (No. S-293 and S-433). All study participants provided written informed consent at the time of enrolment into the parent trials, and all procedures were carried out in accordance with the ethical standards of The Declaration of Helsinki.
: Not applicable.
: The authors declare no conflicts of interest associated with this manuscript.