Funding for this research was provided by:
Israel National Institute for Health Policy Research (2016/80)
EU AIDA (Health-F3-2011-278348)
Received: 25 June 2020
Accepted: 17 March 2021
First Online: 31 March 2021
: The study was approved by the ethics (Helsinki) committee at the Rabin Medical Center and by the local institutional ethics committee at each site. Written informed consent was obtained for all RCT participants. Institutional ethics committee approval numbers: Rambam Health Care Center (Haifa), Israel: 0292–12-RMB. Rabin Medical Center, Beilinson Hospital (Petah-Tikva), Israel: 0236–12-RMC. Tel Aviv Sourasky Medical Center (Tel Aviv), Israel: 0540–12-TLV. Laikon and Attikon Hospitals in Athens, Greece: ΔΥΓ3/89292/2003. Monaldi Hospital, Naples, Italy: Parere CE 1417684.
: Not applicable.
: The authors declare that they have no competing interests.