Funding for this research was provided by:
National Natural Science Foundation of China (81800220)
Hunan province Natural Science Foundation (2019JJ50890)
Hebei Science and Technology Plan Project (17277728D)
Received: 16 May 2019
Accepted: 31 October 2019
First Online: 6 November 2019
Ethics approval and consent to participate
: Written informed consent was obtained from each individual and the investigation was approved by the Institutional Review Board of HeBei General Hospital.
: Written consent was obtained from all the participants or their guardians for the publication of this study.
: The authors declare that they have no competing interests.