Funding for this research was provided by:
National Key R&D Program of China (2018YFC0910500)
National Natural Science Foundation of China (31728012)
Science and Technology Commission of Shanghai Municipality (17DZ22512000)
Lishui medical key disciplines (2016zdxk06)
Zhejiang laboratory animal science and technology (2016C37145)
Received: 16 October 2019
Accepted: 3 December 2019
First Online: 30 December 2019
Ethics approval and consent to participate
: Written informed consent was obtained from all participants or their parents (for minors), and the Ethics Committee of the Sixth Affiliated Hospital of Wenzhou Medical University approved this study.
: Written informed consent was obtained from all participants or their parents (for minors) included in this report for the use of clinical-related materials for scientific research and publications. These materials include medical information, genetic testing results and other related data used in this study.
: The authors declare that they have no competing interests.