Received: 25 August 2019
Accepted: 14 May 2020
First Online: 24 May 2020
Ethics approval and consent to participate
: The families gave informed consent before withdrawal of blood and urine samples and written informed consent was obtained and signed by all studied families: For patients less than 16 years old (P1, P5, P6, P7, P8 and P9), the written consent forms were signed by their parents.In patients older than 16 years (P2, P3, P4, P10, P11 and P12), two subgroups were cited:In patient who are still alive (P2, P3 and P4), the written consent forms were signed by themselves according the available consent form and in the deceased patients (P10, P11 and P12), the written consent forms were signed by themselves when sampling. The patients were later deceased provided consent to participate, before they had passed away.This study was approved by the Ethics Committee of the Fahat Hached Hospital Sousse, Tunisia. All procedures were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 and approved by the Ethics Committees of the respective Tunisian hospitals.
: The deceased patients had provided consent for publication prior to passing away.Written informed consent for publication of their clinical details and/or clinical images was obtained from the parents and patients. Copies of the consent forms are available for review by the Editor of this journal.
: The authors declare that they have no competing interests.