Nouwens, Femke
Visch-Brink, Evy G.
El Hachioui, Hanane
Lingsma, Hester F.
van de Sandt-Koenderman, Mieke W. M. E.
Dippel, Diederik W. J.
Koudstaal, Peter J.
de Lau, Lonneke M. L.
Funding for this research was provided by:
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (017.002.083)
Hersenstichting (2011(1)-20)
Article History
Received: 12 December 2017
Accepted: 7 October 2018
First Online: 15 October 2018
Ethics approval and consent to participate
: SPEAK (MEC-2006-246) and RATS-3 (MEC-2005-347) were approved by the Medical Ethical Committee of Erasmus MC University Medical Center. According to Dutch regulation monitored by the Central Committee on Research Involving Human Subjects local sites formally approved their participation: Bronovo Hospital The Hague, Canisius-Wilhelmina Hospital Nijmegen, Deventer Hospital, Gelre Hospital Zutphen, Haga Hospital The Hague, Kennemer Gasthuis Haarlem, Maasstad Hospital Rotterdam, MCH The Hague, St. Elisabeth Tilburg, Tergooi Hospitals Laren and Blaricum, TweeSteden Hospital Tilburg, UMC St. Radboud Nijmegen, Bernhoven Hospital Oss, Rijnstate Hospital Zevenaar, Diaconessenhuis Meppel, Haven Hospital Rotterdam, Sint Franciscus Gasthuis Rotterdam, Ikazia Hospital Rotterdam, Vlietland Hospital Schiedam, IJsselland Hospital Capelle aan den IJssel, Reinier de Graaf Gasthuis Delft, VUMC Amsterdam, Beatrix Hospital Gorinchem, Amphia Hospital Breda, Onze Lieve Vrouwe Gasthuis Amsterdam, Sint Lucas Andreas Hospital Amsterdam, Catharina Hospital Eindhoven, Franciscus Hospital Roosendaal, Isala Klinieken Zwolle, Jeroen Bosch Hospital Den Bosch, Erasmus MC Rotterdam, Trappenberg Huizen, Leijpark Rehabilitation Tilburg, Tolbrug Rehabilitation Den Bosch, RMC Groot Klimmendaal Ede, Sint Maartenskliniek Nijmegen, Sophia The Hague, Sutfene Warnsveld, Amaris Gooizicht Hilversum, Regina Pacis Arnhem, Gelders Hof Arnhem, Watersteeg Veghel, Den Ooiman Doetinchem, Hazelaar Tilburg, Boerhaave Haarlem, Cortenbergh Renkum, Zuiderhout Haarlem, Sint Jozef Deventer, Waelwick Ewijk, Irene Dekkerswald Groesbeek, Margriet Nijmegen, Bonnier-Baars Practice Heesch, Laurens Antonius Rotterdam, Rijndam Rehabilitation Rotterdam, Centrum voor Reuma en Revalidatie Rotterdam, Zonnehuis Vlaardingen, Stichting Pieter van Foreest Delft, Florence The Hague, Zonnehuis Amstelveen, Reade Amsterdam, De Volckaert-SBO Oosterhout, Stichting Elisabeth Breda, Thebe Aeneas Breda, De Riethorst-Stromenland Geertruidenberg, Stichting de Bilthuysen Bilthoven, Zorgcombinatie Noorderboog Reggersoord Meppel, Stichting Groenhuysen Roosendaal, Avoord Zorg en Wonen Etten-Leur, Stichting SHDH Janskliniek Haarlem, Stichting Afasietherapie Amsterdam, Rivas Gorinchem, Aafje Rotterdam, De Zellingen Rijckehove Rotterdam, Saffier de Residentie Mechropa The Hague, Respect Zorggroep Scheveningen The Hague, Revant Rehabilitation Breda, Surplus Zorg Zevenbergen, Careyn Spijkenisse, De Vogellanden Zwolle, De Hoogstraat Utrecht, Woonzorgconcern IJsselheem Zwolle, Osira Amsterdam, Stichting Sint Jacob Jacobkliniek Haarlem, Viattence De Wendhorst Heerde, Zonnehuisgroep IJssel-Vecht Zwolle, Zorgbalans Driehuis, Novicare Best, Libra Zorggroep Blixembosch Eindhoven, Logopedie Zandvoort Zandvoort, Practice M.P. de Boer Haarlem, Brabantzorg Ammerzoden, Zorggroep Elde Boxtel, Van Neynselgroep Den Bosch, Vivent Rosmalen.Participants and/or their proxies gave written informed consent to participate in the original studies. All SL-therapists and research team members that were involved in the informed consent procedure for these studies were instructed to always include patients and their proxies in the process. Consequently, candidates could discuss their participation with someone they trusted and proxies of the candidate also approved participation. The only exception was when candidates did not have a next of kin. If baseline tests showed a severe aphasia, these patients were not deemed eligible to provide informed consent solely.In addition to information provided in one or more conversations, candidates were provided with information leaflets containing all details of the studies; one leaflet with all information for the proxies and one simplified “aphasia friendly” version.The informed consent procedure and materials used were approved by het Medical Ethical Committee of Erasmus MC University Medical Center.By consenting to participate in SPEAK and RATS-3 participants also approved that their anonymized data could be used in post-hoc analyses. Hence, additional consent for this study was not necessary.
: Not applicable.
: HEH, EV and MS receive royalties from the ScreeLing, a linguistic screening tool, used as a variable in the prognostic model. The other authors report no disclosures.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.