Received: 15 February 2020
Accepted: 10 May 2020
First Online: 19 May 2020
Ethics approval and consent to participate
: The studies in this integrated safety analysis were conducted in concordance with the ethical principles that have their origin in the Declaration of Helsinki guidelines. All patients provided written informed consent before study participation.The study protocols, for all four studies, were reviewed and approved by the Institutional Review Board, Medical Ethics Committee or Medical Research & Ethics Committee of the participating study sites (Additional file InternalRef removed).
: Not applicable.
: Eli Lilly and Company funded the studies in whole. VLS, SW, RB, KAD and AC reported being full-time employee of Eli Lilly and Company. SW and AC also report being minor shareholders of Eli Lilly and Company. JB reported receiving ancillary supplies, clinical grant, food and beverage, lodging, transportation and travel grant from Eli Lilly and company. BK reports receiving personal fees from Eli Lilly and Company, TEVA, Novartis, Sanofi Korea, Allergan Korea, Lundbeck Kora, SK chemical, GSK Korea.