Received: 16 June 2020
Accepted: 17 November 2020
First Online: 26 November 2020
Ethics approval and consent to participate
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. After approval of the protocol by the local standing committee on ethical practice of the University of Heidelberg (Approval Number S-642/2018), written informed consent was obtained from all individual participants or their legal guardians included in the study. Ethics Committee of the Medical Faculty, University of Heidelberg, Heidelberg, Germany, Approval Number S-642/2018
: Not applicable.
: All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.