Hatano, Taku http://orcid.org/0000-0002-6808-0444
Kano, Osamu
Sengoku, Renpei
Yoritaka, Asako
Suzuki, Keisuke
Nishikawa, Noriko
Mukai, Yohei
Nomura, Kyoichi
Yoshida, Norihito
Seki, Morinobu
Matsukawa, Miho Kawabe
Terashi, Hiroo
Kimura, Katsuo
Tashiro, Jun
Hirano, Shigeki
Murakami, Hidetomo
Joki, Hideto
Uchiyama, Tsuyoshi
Shimura, Hideki
Ogaki, Kotaro
Fukae, Jiro
Tsuboi, Yoshio
Takahashi, Kazushi
Yamamoto, Toshimasa
Yanagisawa, Naotake
Nagayama, Hiroshi
Funding for this research was provided by:
Kyowa Kirin Co., Ltd.
Article History
Received: 14 October 2020
Accepted: 23 February 2022
First Online: 3 March 2022
Declarations
:
: This study complies with the Japan Clinical Trials Act and all relevant national and international guidance for the conduct of human trials, and with the Declaration of Helsinki. The study protocol (Version 4.1, 14 March 2019) and all other study documentation were reviewed and approved by the Juntendo University Certified Review Board (J18-006), approval number CRB3180012. All patients are providing or have provided written informed consent prior to participation. All patient data are anonymized; data obtained from the wearable device will not specify any personal information.
: Not applicable.
: This study is funded by Kyowa Kirin Co., Ltd., Tokyo, Japan (commercial organization). The funding organization has implemented a peer review process of the study protocol.TH is an associate editor/member of the editorial board for BMC Neurology and reports receiving grants and honoraria or consultation fees from Kyowa Kirin Co., Ltd. during the conduct of the study.OK reports grants and consultation fees from Kyowa Kirin Co., Ltd. during the conduct of the study.RS is an associate editor/member of the editorial board for BMC Neurology and reports grants and consultation fees from Kyowa Kirin Co., Ltd. during the conduct of the study.AY reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study; and reports grants from Eisai Co., Ltd. and Sumitomo Dainippon Pharma, outside the submitted work.KS is an editorial board member of BMC Neurology, and reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.NN reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.YM reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.KN reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.NYo reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.MS reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study; and received a Takeda Japan Medical Affairs Funded Research Grant 2018, and grants from Kanae Foundation for the promotion of medical science, outside the submitted work.MM reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.HT reports grants and personal fees from Kyowa Kirin Co., Ltd. during the conduct of the study.KK reports grants and personal fees from Kyowa Kirin Co., Ltd. during the conduct of the study; and personal fees from Medtronic, Boston Scientific, Ono Pharmaceuticals Co., Ltd., Otsuka Pharmaceuticals Co., Ltd., AbbVie GK, Eisai Co., Ltd., Takeda Pharmaceuticals Co., Ltd., and Sumitomo Dainippon Pharma, and grants from Novartis AG, outside the submitted work.JT reports grants and non-financial support from Kyowa Kirin Co., Ltd. during the conduct of the study; and personal fees and non-financial support from Kyowa Kirin Co., Ltd., Takeda Pharmaceutical Co., Ltd., Sumitomo Dainippon Pharma Co., Ltd., and FP Pharmaceutical Corporation, and non-financial support from Eisai Co., Ltd. and AbbVie GK outside the submitted work.SH reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study; and grants from Eli Lilly Japan K.K., and grants and lecture fees from Nihon Medi-Physics Co., Ltd. outside the submitted work.HM reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.HJ reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.TU reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.HS reports grants and lecture fees from Kyowa Kirin Co., Ltd. during the conduct of the study.KO reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.JF reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.YT reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.KT reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.TY reports grants from Kyowa Kirin Co., Ltd. during the conduct of the study.NYa reports grants and consultant fees from Kyowa Kirin Co., Ltd. during the conduct of the study.HN reports grants and consultant fees from Kyowa Kirin Co., Ltd. during the conduct of the study.