Funding for this research was provided by:
Medical Research Council (MR/M013960/1, MR/N013794/1)
Biotechnology and Biological Sciences Research Council (BB/M009122/1)
Received: 6 March 2020
Accepted: 22 December 2020
First Online: 10 January 2021
Ethics approval and consent to participate
: Full ethical approval for the GiW Study cohort was obtained from the Wales Research Ethics Committee REC reference 15/WA/0004. Research was performed in line with the principles of the Declaration of the Helsinki as revised in 2008. Written informed consent was obtained from all the participants at recruitment.
: Not applicable.