Funding for this research was provided by:
National Natural Science Foundation of China (81471473)
Chongqing Health Planning Commission project (2019ZDXM055)
Received: 24 March 2022
Accepted: 20 November 2022
First Online: 8 December 2022
: Both animal and human experiments in this study were approved by the ethical committee of the First Affiliated Hospital of Chongqing Medical University (Ethical Application Ref: 2021–533). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All participants signed a written informed consent form prior to their participation in this study.The methods are reported in accordance with ARRIVE guidelines for the reporting of animal experiments. All animal experimental protocols have been carried out in accordance with relevant guidelines and regulations.
: Not applicable.
: The authors who have taken part in this study declared that they do not have anything to disclose regarding funding or conflict of interest with respect to this manuscript.