Funding for this research was provided by:
Dietmar-Hopp Stiftung (23011184)
Deutsche Forschungsgemeinschaft and Ruprecht-Karls-Universität Heidelberg within the Open Access Publishing funding program (IN-1150438)
Article History
Received: 21 January 2017
Accepted: 24 August 2017
First Online: 1 September 2017
Ethics approval and consent to participate
: The study was approved by the ethics committee of the Medical University in Heidelberg (Ethic commission S-141/2008 Medical Faculty). Patients for this study were identified in two different ways. The first part of the patient cohort were patients who took part in a previous prospective case-control study between 1998 and 2000. Here, patients gave their written informed consent including a long term follow-up (Ethic commission 135/97/1997 Medical Faculty). Written informed consent was obtained from the participants through collaborating physicians. For patients who were identified retrospectively (2001–2004), no written consent was required (Ethic commission S-141/2008 Medical Faculty).
: Not applicable.
: The authors declare that they have no competing interests.
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