Funding for this research was provided by:
National Natural Science Foundation of China (81471065, 81770838, 31470856, 91439124, 81101982)
Shandong Province (2016GSF201005, 2013GSF12121)
Received: 6 November 2017
Accepted: 1 March 2018
First Online: 6 March 2018
Ethics approval and consent to participate
: All human and animal study protocols were approved by Ethical Review Board of Shandong University. For study on human tissue arrays obtained from Outdo Biotech Co., Shanghai, China, informed consent has been waived by Ethical Review Board of Shandong University. All animal-related procedures were in accordance with the institutional guidelines for animal care and utilization.
: Not applicable.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.