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The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes

Crossref DOI link: https://doi.org/10.1186/s12885-018-4221-0

Published Online: 2018-03-22

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Matsushita, Junya

Okamura, Kazuyuki

Nakabayashi, Kazuhiko

Suzuki, Takehiro

Horibe, Yu

Kawai, Tomoko

Sakurai, Toshihiro

Yamashita, Satoshi

Higami, Yoshikazu

Ichihara, Gaku

Hata, Kenichiro

Nohara, Keiko http://orcid.org/0000-0001-6529-3316
Funding

Funding for this research was provided by:

Ministry of Education, Culture, Sports, Science and Technology of Japan (26293154)

Ministry of Education, Culture, Sports, Science and Technology of Japan (15K15246)

National Institute for Environmental Studies (1115AA082, 1315AT001, 1620AA041)
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Article History

Received: 5 October 2017

Accepted: 13 March 2018

First Online: 22 March 2018

Ethics approval and consent to participate

: Animal studies were permitted by the Animal Care and Use Committee of National Institute for Environmental Studies (NIES) and were performed in accordance with guideline for the Care and Use of Laboratory Animals of NIES.The results on human HCC shown in Fig.InternalRef removedare based on existing data generated by The Cancer Genome Atlas project established by the NCI and NHGRIExternalRef removed. New experimental material was not used in this study.

: Not applicable.

: The authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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