Funding for this research was provided by:
roche pharma ag
Received: 8 August 2017
Accepted: 21 March 2018
First Online: 8 May 2018
Ethics approval and consent to participate
: All procedures performed in this study were in accordance with the ethical standard of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study was approved by the local ethical committees of the following institutions: University of Duesseldorf, University of Erlangen, University of Essen, University of Freiburg, University of Hamburg, University of Munich, University of Heidelberg, University of Regensburg and University of Tuebingen.
: Not applicable.Informed consent: Written informed consent was obtained from all individual participants included in this study.
: The authors declare that they have no competing interests.
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