Funding for this research was provided by:
National Natural Science Foundation of China (81472618, 81670535, 31100895, 81402297, 31771401)
Hong Kong Health and the Medical Research Fund (01121436)
the National Science and Technology Major Project (2018ZX10301202)
the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (No. 2017BT01S131)
the Innovative Research Team Project of Guangxi Province (2017GXNSFGA198002)
the Outstanding Youths Development Scheme of Nanfang Hospital, Southern Medical University (No. 2017J001)
the National Science and Technology Major Projec (No. 2017ZX10202202)
the Key-Area Research and Development Program of Guangdong Province (2019B020227004)
Received: 31 August 2019
Accepted: 7 April 2020
First Online: 11 May 2020
Ethics approval and consent to participate
: The study was performed in accordance with guidelines approved by the local ethical committees from all participating centers involved in both the GWAS stage (the ethics committee of Qidong Liver Cancer Institute) and the replication stage (the ethics committee of the Second Military Medical University). A written informed consent to participate in the study was obtained from each subject in accordance with the declaration of Helsinki principles. All study participants approved the storage of their frozen DNA specimens, for research purposes, in our laboratory.
: Not applicable.
: The authors declare that they have no conflict of interest.