Funding for this research was provided by:
Received: 27 September 2019
Accepted: 6 June 2020
First Online: 12 June 2020
Ethics approval and consent to participate
: The current study has been approved by the Certified Review Board of Keio (CRB3180017), and permission for conducting the study has been obtained from the managements of all participating facilities. Written informed consent for participation will be obtained from participants. Separate written informed consent will be obtained for the assessment of RAM pharmacokinetics and correlative research.
: Not applicable.
: Yasuo Hamamoto is an Associate Editor of this journal. The other authors declare that they have no competing interests.