Received: 10 March 2021
Accepted: 9 July 2021
First Online: 16 July 2021
: All methods were carried out in accordance with relevant guidelines and regulations. This study was approved by the ethics committees (institutional review boards) at Duke University, Durham VA, and VA Salt Lake City. The institutional review boards authorized a waiver of informed consent.
: Not applicable.
: All authors report the research grant from AstraZeneca for this study. Dr. Kelley reports personal fees from Eisai, grants from Bavarian Nordic, grants from Novartis, grants from Bristol-Myers Squibb, grants from Regeneron, other from IBM, and personal fees from IBM Japan, outside the submitted work. Dr. Reed reports personal fees from AstraZeneca, outside the submitted work. Dr. Hung reports grants from PhRMA, and personal fees from Blue Cross Blue Shield Association and CVS Health outside the submitted work. Drs. Yong and Seal are employees of AstraZeneca. Dr. Buckingham was an employee of AstraZeneca during time of study and is currently employed by GSK.