De Caluwé, Alex http://orcid.org/0000-0001-5989-7017
Buisseret, Laurence
Poortmans, Philip
Van Gestel, Dirk
Salgado, Roberto
Sotiriou, Christos
Larsimont, Denis
Paesmans, Marianne
Craciun, Ligia
Stylianos, Drisis
Vandekerckhove, Christophe
Reyal, Fabien
Isabelle, Veys
Eiger, Daniel
Piccart, Martine
Romano, Emanuela
Ignatiadis, Michail
Funding for this research was provided by:
AstraZeneca
Article History
Received: 6 October 2020
Accepted: 14 July 2021
First Online: 6 August 2021
Declarations
:
: Clinical research was performed in accordance with the Declaration of Helsinki and the protocol was approved by ethical committees in Belgium and France. In Belgium: Commissie Medische Ethiek UZ Brussels/VUB, Laarbeeklaan 101, 1090 Brussels, Reference number: 2019/P/02. In France: Ethics committee: CHU de Grenoble, Comité de Protection des personnes, CS 10217 38043, Grenoble Cedex 9, Reference number: 08. Réf. CPP: 20-JUBO-01.Informed consent to participate in the study will be obtained from all participants.
: This present manuscript does not contain any patient data because only the trial protocol is described, hence consent for current publication is not applicable. The patients that are currently being included in the trial provide written consent for publication of trial results after reading and understanding an informed consent form.
: ADC: institutional research grant from AstraZeneca. LB: institutional research grant from AstraZeneca; speaker honoraria from BMS; travel grant from Roche. PP: part-time medical advisor for Sordina IORT Technologies s.p.a., since 1 April 2020, not related to this work. DVG: Advisory board/Honoraria received: Sanofi, Accuray, Merck-Pfizer, Takeda and Novartis. RS: non-financial support from Merck, non-financial support from BMS, other from Puma Biotechnology, other from Roche, other from Roche, other from Merck. DE: Research Funding (ESMO Fellowship): Novartis. Speaker fee: Janssen. MP: Board Member (Scientific Board): Oncolytics; Consultant (honoraria): AstraZeneca, Camel-IDS, Crescendo Biologics, Debiopharm, G1 Therapeutics, Genentech, Huya, Immunomedics, Lilly, Menarini, MSD, Novartis, Odonate, Periphagen, Pfizer, Roche, Seattle Genetics. Research grants to my Institute: AstraZeneca, Lilly, MSD, Novartis, Pfizer, Radius, Roche-Genetech, Servier, Synthon. No stock ownership. ER: no disclosures relevant to this project. MI: Consultant or advisory role (honoraria): Celgene, Novartis, Pfizer, Seattle Genetics, Tesaro. Research grants to my Institute: Roche, Menarini Silicon Biosystems, Janssen Diagnostics, Pfizer. No stock ownership. Travel grants: Pfizer, Amgen. All other authors: no competing interests disclosed.