Funding for this research was provided by:
Jiangsu Provincial Special Program of Medical Science (BE2019710)
Major Project of Jiangsu Provincial Commission of Health (DZ2021038)
Changzhou Municipal Social Development Program (CE20195001)
Yangzhou Municipal Social Development Program (YZ2020069)
Scientific and Technologic Development Program of Suzhou (SYS2019007)
Received: 8 April 2022
Accepted: 24 October 2022
First Online: 28 October 2022
: This project has been registered on chineseclinicaltrials.gov (ChiCTR1900028524). The protocol is in accordance with the ethical guidelines of the 1975 Declaration of Helsinki, as reflected by prior approval by two Chinese tertiary academic hospitals (2019ZDSYLL092-P01 from Zhongda Hospital Southeast University, 2020-YKL04-008 and 2021YKL-07–20-02 from the Affiliated Hospital of Yangzhou University) and two tertiary local hospitals (2019020 from Changshu No.2 People’s Hospital, the Affiliated Changshu Hospital of Xuzhou Medical University, KY-2019003 from Jintan Hospital Affiliated to Jiangsu University).All participants will be informed that their anonymous data will be used for research and publication. Relevant information of this project will be provided to potential eligible participants in oral and written forms for them to make their decisions of participation or not. Each participant will be informed that he/she can withdraw from the study at any time and that withdrawal will not affect his or her subsequent medical treatment.
: Written consent for publication from each participant is mandatorily required. Results will be disseminated to the scientific community through peer-reviewed journal articles and international conference presentations.
: The authors declare that there is no competing interest. Mrs. Xinxi Xu, Mr. Guangpeng Xu and Ms. Juncai Zang are employees of Foreasy Tech Co. They are main members of the project of Jiangsu Provincal Special Program of Medical Science (BE 2019710). They do not have any financial arrangement for this research or the preparation of this manuscript.