Funding for this research was provided by:
Health Technology Assessment Programme (14/49/34)
Text and Data Mining valid from 2020-04-14
Received: 13 December 2019
Accepted: 11 March 2020
First Online: 14 April 2020
Ethics approval and consent to participate
: All procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008. All participants gave written informed consent and all procedures were approved by Lancaster National Research Ethics Service committee (15/NW/0732).
: Not applicable.
: Some members of the applicant team (FL, SJ1, SJ2, LC) were involved in developing REACT. This study is therefore not an independent evaluation. BH has been a NIHR HS&DR commissioned board member and PW reports additional grants from NIHR for other studies, and NIHR funding for The Clinical Trials Research Centre during conduct of this study.