Funding for this research was provided by:
Dunhill Medical Trust (R431/0715)
Received: 15 November 2018
Accepted: 21 May 2020
First Online: 2 June 2020
Ethics approval and consent to participate
: Both the C4C trial (reference: 16/NW/0757) and the REACT trial (reference: 15/NW/0732) received ethical approval from the North-West Lancaster NHS Research Ethics Committees. Participants in both the C4C trial and REACT trial provided written informed consent for their data to be used within research reports, and for their anonymous data to be shared with other research teams for research purposes.
: Not applicable.
: The authors declare that they have no competing interests.