Received: 8 November 2021
Accepted: 19 April 2022
First Online: 15 June 2022
: The patients who donated the samples have signed informed consent, and the project was approved by the Ethics Committee of The First Affiliated Hospital of Zhejiang University Hospital.
: All authors have read and agreed with the submission of the manuscript. This manuscript has not been published or presented elsewhere in part or in entirety. There are no conflicts of interest to declare. This manuscript was not pre-registered.
: All authors declare no conflict of interest.