Funding for this research was provided by:
Instituto de Salud Carlos III (PI18/00915)
Received: 16 August 2019
Accepted: 29 August 2019
First Online: 4 September 2019
Ethics approval and consent to participate
: Participants will be informed about the content, purpose, and procedure of the study by means of a written form of informed consent. No negative impact on the study participants is expected.The study will be conducted in accordance with the principles of the Helsinki Declaration, and will follow Spain’s best practice guidelines (Buena Práctica Clínica). Data confidentiality will be protected under the Spanish law governing the protection of personal data (Ley Orgánica 3/2018 de Protección de Datos de Carácter Personal).Ethics approval was obtained from the Ethics Committee of Institut d’Atenció Primària Jordi Gol (reference coder: P18/208) and from the Institut d’Investigacions Sanitàries Pere Virgili (reference code CEIM: 186/2018). These Ethical Approvals cover all the participating sites included in this study.
: Not applicable as the manuscript does not contain any individual person’s data which is not from the research group.
: The authors declare that they have no competing interests.