Funding for this research was provided by:
Medical Research Council
Cancer Research UK
British Heart Foundation
US Centers for Disease Control and Prevention Foundation
NIHR Oxford Biomedical Research Centre
BHF Centre of Research Excellence, Oxford
Received: 28 January 2021
Accepted: 26 April 2021
First Online: 27 May 2021
: Ethics approval was provided by the Ethics Committee of the National Institute of Cardiology and Cardiac Surgery, Havana (ref: 0404134). All participants provided written informed consent.
: Not applicable.
: SL reports grants from the Medical Research Council (MRC) during the conduct of the study, and research funding from the US Centers for Disease Control and Prevention Foundation (with support from Amgen). JE reports a grant from Boehringer Ingelheim outside of the submitted work. All other authors declare no competing interests.