Received: 16 July 2021
Accepted: 14 December 2021
First Online: 13 January 2022
: The EPOCH 1 and EPOCH 2 instruments were approved by the Hamilton Health Sciences/McMaster Health Sciences Research Ethics board, which operates in compliance with the ICH Good Clinical Practice Guidelines, the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans, and Division 5 Health Canada Food and Drug Regulations. Ethics approvals were obtained at each study centre, and all participants provided written informed consent.
: Not applicable.
: The authors declare that they have no competing financial or non-financial interests.