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Article History

Received: 21 July 2020

Accepted: 15 September 2020

First Online: 21 September 2020

Ethics approval and consent to participate

: The study was reviewed and received approval by the local ethics committee of Fondazione Policlinico Universitario “A. Gemelli” IRCCS in Rome. The need to receive an informed consent from all patients was waived due to the retrospective nature of the study.

: Not applicable.

: Dr. Sgalla reports personal fees from Boheringer Ingelheim oustide the submitted work; Dr. Calvello reports personal fees from Boehringer Ingelheim, outside the submitted work; Dr. Varone reports personal fees from Boehringer Ingelheim, personal fees from Roche, outside the submitted work; Dr. Iovene reports personal fees from Menarini, personal fees from Boehringer Ingelheim, outside the submitted work; Dr. Richeldi reports personal fees and other from Boehringer Ingelheim, grants and personal fees from InterMune, personal fees from Cipla, personal fees from Vertex, other from AstraZeneca, other from GlaxoSmithKline, other from Sanofi-Aventis, other from Celgene, other from Prometic, other from Roche, other from Takeda, during the conduct of the study. The rest of the authors declare no further competing interests.