Funding for this research was provided by:
Japan Society for the Promotion of Science (JP17K09619)
Received: 19 July 2019
Accepted: 23 January 2020
First Online: 31 January 2020
Change Date: 7 May 2020
Change Type: Correction
Change Details: Following publication of the original article , the authors have flagged that there is an error in Fig. 3.
Ethics approval and consent to participate
: This study was conducted in accordance to the Declaration of Helsinki and was approved by the Institutional Review Board of Sapporo Medical University School of Medicine (approval number: 302–120, dated November 8, 2018). For this type of study, formal consent is not required.
: Not applicable.
: HC has served as a speaker for Boehringer Ingerheim; HT has received grants from Boehringer Ingerheim and Shionogi, and also has served as a speaker for Boehringer Ingerheim.