Funding for this research was provided by:
Novartis Pharma Research Grants
Japan Society for the Promotion of Science (19K23610)
Received: 15 November 2021
Accepted: 18 April 2022
First Online: 8 May 2022
: This study was conducted in accordance with the declaration of Helsinki and was approved by the institutional ethical committee of Sapporo Medical Association. The experimental protocols and the purpose of the research were explained to all participants and informed consent was obtained in the form of opt-out on the website.
: Not applicable.
: None of the authors have a conflict of interest to declare.