Funding for this research was provided by:
National Natural Science Foundation of China (No.81772298)
National Natural Science Foundation of Hunan Province, China (No.2018JJ3848, No.2017JJ3338)
National Key Research and Development Program of Hunan Province, China (No.2017SK2062)
Received: 21 March 2019
Accepted: 9 October 2019
First Online: 25 October 2019
Ethics approval and consent to participate
: This study has been conducted adhering to the principles of the Declaration of Helsinki II and approved by the medical ethics committee of Xiangya Hospital, Central South University (ethical code: 201703358). Written informed consent was obtained from all the study participants or their parent or guardian respectively.
: Not applicable.
: The authors declare that they have no competing interests.