Funding for this research was provided by:
National Natural Science Foundation of China (81772434)
Guangzhou Municipal Science and Technology Project (201704020122)
Received: 10 December 2019
Accepted: 3 August 2020
First Online: 22 August 2020
Ethics approval and consent to participate
: The study protocol was reviewed and approved by the Human Subjects Ethics Sub-committee of the First Affiliated Hospital, Sun Yat-sen University (Approval number:  C-034). All subjects gave written informed consent. The study was conducted in accordance to the Declaration of Helsinki.
: Written informed consent was obtained from all participants for the publication of the data present in the manuscript.
: The authors declare that they have no competing interests. The authors have no financial relationship with the manufacturer of the used in the present study.