Funding for this research was provided by:
Agency for Healthcare Research and Quality (R01HS024714, R01HS024714, R01HS024714)
Received: 11 May 2022
Accepted: 19 October 2022
First Online: 27 October 2022
: (a) All procedures were performed in accordance with the relevant ethical guidelines and regulations. (b) This study was approved by the central (single) human subjects review board from the Medical University of South Carolina (Pro00053742). Written informed consent was obtained from all participants.
: Not Applicable.
: One or more of the authors (HK, CP, BM) have received funding from Agency for Healthcare Research and Quality (AHRQ). CP received royalties from Total Joint Orthopedics and research support from Zimmer Biomet. CP served as a paid consultant for Simith & Nephew, Total Joint Orthopedics, Zimmer Biomet, 3 M, Haereus, and Immunis. CP holds stock in Joint Development LLC. BM served as a paid consultant on the PEPPER trial, through ownership in STATIX, LLC. VP has nothing to disclose. The PEPPER INVESTIGATORS do have any competing interest.