Funding for this research was provided by:
Stiftung Endoprothetik (S 01/18, S 01/18, S 01/18, S 01/18)
Received: 2 October 2022
Accepted: 9 January 2023
First Online: 21 January 2023
: This study was performed in accordance with the Declaration of Helsinki and approved by the local Ethics Committee (Ethikkommission der Medizinischen Fakultät Heidelberg, reference S-351/2018). The tissue samples were obtained from Science Care (Phoenix, AZ, USA), which is accredited by the American Association of Tissue Banks, and receives informed donor consent from all subjects and/or their legal guardian(s) prior to sample acquisition.
: Not applicable.
: N.A.B. has received research support from the Deutsche Arthrose Hilfe e.V. for an unrelated project. T.R. has received research support and personal fees from Arbeitsgemeinschaft Endoprothetik (AE), DGOU, DGOOC; BVOU, DePuy International, Otto Bock Foundation, Deutsche Arthrose Hilfe, Aesculap, Zimmer, Stiftung Oskar Helene Heim Berlin, Vielberth Foundation Regensburg, the German Ministry of Education and Research as well as the German Federal Ministry of Economic Cooperation and Development. He is Medical Director and Chair at the Orthopaedic Department at Heidelberg University Hospital, board member of the German Society for Orthopaedics and Trauma (DGOOC) and vice president of the Professional Association of Orthopaedic Specialists and Trauma Surgeons (BVOU). S.J. reports grants from B Braun Aesculap, Johnson & Johnson Depuy Synthes, Heraeus Medical, Waldemar Link, Peter Brehm, Implantcast, Ceramtec, Mathys, Tornier/Stryker and Zimmer Biomet that are not related to the current study. The remaining authors have no conflicts to declare. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.