Funding for this research was provided by:
National Institute on Drug Abuse (R43DA044064)
Antidote Therapeutics, Inc.
Received: 30 April 2018
Accepted: 12 July 2018
First Online: 24 July 2018
Ethics approval and consent to participate
: These studies were performed in accordance with the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. Animal protocols were approved by the Minneapolis Medical Research Foundation Animal Care and Use Committee and by the Noble Life Sciences Animal Care and Use Committee. Animals were euthanized by CO<sub>2</sub> inhalation using AAALAC approved chambers, and all efforts were made to minimize suffering.
: Not applicable
: ZB, TT, and MWK are employees of Antidote Therapeutics, Inc.; SH is an employee of Noble Life Sciences.
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