Funding for this research was provided by:
European Regional Development Fund (188.8.131.52/16/A/066)
Text and Data Mining valid from 2020-01-29
Received: 13 March 2019
Accepted: 16 January 2020
First Online: 29 January 2020
Ethics approval and consent to participate
: The patient was recruited to the LGDB, a government-funded national biobank, by an endocrinologist at Pauls Stradins Clinical University Hospital, Riga, Latvia in 2010. LGDB is a central institution for human genetic material biobanking for research needs in Latvia [CitationRef removed]. Two written informed consents were obtained from the patient, broad consent for LGDB for use of biological material and medical data for human health and hereditary research, and project-specific consent with approval of the use of biological material and clinical data in research related to pituitary tumours that included all procedures and analyses described in this manuscript. In addition, upon request from the journal, a specific written informed consent to publish the results as a case report was obtained prior to publication. Both the biobank study design and PA research study and both written informed consents obtained from the patient have been approved by the Central Medical Ethics Committee of Latvia (protocol No. 22.03.07/A7 and 01.29.1/28, respectively). The sample collection and research process comply with the Declaration of Helsinki (in particular parts A and B) and the Declaration of Taipei.
: The patient has consented to the national biobank Genome Database of the Latvian population design approved by the Central Medical Ethics Committee of Latvia (protocol No. 22.03.07/A7) and pituitary adenoma research approved by the Central Medical Ethics Committee of Latvia (protocol No. 01.29.1/28). Both consents imply the use of the samples for health research, which includes reporting and confidentiality topics. The Institutional Review Board of Latvian Biomedical Research and Study Centre (Scientific Council) has evaluated the compliance of obtained consents and results of the study and has approved this study to be published as case report. Specifically, informed consent was obtained also from the patient for the specific publication of this manuscript.
: The authors declare that they have no competing interests.