Funding for this research was provided by:
Bio Minerals NV
Received: 30 November 2020
Accepted: 8 September 2021
First Online: 29 September 2021
: Written informed consent was obtained from all patients prior to randomization. The study was approved by the local Ethical Committee of the Cukurova University, Adana, Turkey (65/4, 04.05.2017).
: Not applicable.
: SMP and IDC are employed as research associates of the study sponsor Bio Minerals NV (Belgium, the manufacturer of choline-stabilized orthosilicic acid). MCH has received financial support from Bio Minerals NV to conduct the study. WT, GUC and MT report no conflicts of interest related to this study.