Yao, Wenming
Cheang, Iokfai
Liao, Shengen
Zhou, Yanli
Zhou, Fang
Xu, Dongjie
Jia, Zhenhua
Chang, Liping
Zhang, Haifeng
Li, Xinli http://orcid.org/0000-0002-6794-1468
Funding for this research was provided by:
National Key R&D Program of China (2017YFC1700505, 2017YFC1700501)
the Major Program of the National Natural Science Foundation of China (81730106)
Article History
Received: 12 June 2019
Accepted: 20 January 2020
First Online: 5 February 2020
Ethics approval and consent to participate
: All participating centers must obtain approval from appropriate independent ethics committees or institutional review boards (Approved No. of ethic committee: 2018-SR-275). The study will be conducted in accordance with the principles of Good Clinical Practice and the Declaration of Helsinki. The trial was registered at http://www.chictr.org.cn - ChiCTR1900021929. All participants must give written informed consent (Additional file InternalRef removed) which should be acquired after sufficient and detailed explanation to research situation (including confidentiality, risk and benefits, purpose of the study, etc.).
: Not applicable.
: The operation of the program has undergone peer-review by the funding body for budget review. The design of the study, data collection, data analysis and interpretation are independent to the funding body.All executive committee members have received consulting fees as well as travel and research support in the planning and conduct of the QUEST study. The authors declare that they have no other conflict of interest to disclose.