Received: 13 January 2021
Accepted: 5 April 2021
First Online: 8 June 2021
: Animal experimental procedures were approved by the institutional Ethical Committee for Animal Experimentation at the Faculty of Pharmacy, Cairo University, Cairo, Egypt, approval number (PT 1769) following the guidelines laid out in the Guide for the Care and Use of Laboratory Animals, National Academy of Science.
: Not applicable.
: The authors RMA, SR and HA were employed by Bayer Consumer Health, Darmstadt, Germany. They were kind enough to consent to the proposed study presented to the company and to help in revising the manuscript. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.