Wang, Man
Geng, Xufang
Li, Kaipeng
Wang, Yawen
Duan, Xiaofeng
Hou, Congcong
Zhao, Lili
Zhou, Huimin
Zhao, Ding
Funding for this research was provided by:
Department of Education of Hebei Province (17967753D)
Article History
Received: 5 March 2022
Accepted: 4 July 2022
First Online: 25 July 2022
Declarations
:
: Rats were purchased from the Experimental Animal Center of Hebei Medical University (China). They were housed in groups of four and given three days to acclimate to the housing facility. The environmental conditions were a temperature of 21 °C ± 2 °C, humidity of 55% ± 10% and a 12:12 light: dark cycle with lights on at 07:00 and off at 19:00. Animals were housed in 600 × 400 × 300 mm cages and given access to rat maintenance food and water ad libitum. During housing, animals were monitored twice daily for health status. No adverse events were observed. All animals were handled in accordance with our institutional guidelines for animal care, as well as with the National Institutes of Health guidelines regarding the care and use of animals for experimental procedures. The present study was approved by the Hebei Medical University Ethics Committee for Animals (SYXK (Ji) 2020–002). The study was conducted in compliance with the ARRIVE guidelines.
: Not applicable.
: The authors declare that they have no conflicts of interest to report.