Funding for this research was provided by:
National Institute on Aging (R01 AG033035)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (K24 AR062133)
Received: 26 October 2017
Accepted: 27 August 2019
First Online: 18 September 2019
Ethics approval and consent to participate
: This study was approved by the ethics committee at all three sites by the University of Iowa Human Subjects Office and the Kaiser Permanente Institutional Review Board. Written consent was obtained from participants from the University of Iowa and verbal consent was obtained from Kaiser Permanente participants based on policies of each institution’s human subjects’ office.
: Not applicable.
: The authors declare that they have no competing interests with publication of this manuscript. Dr. Wright has received unrestricted grant support from Amgen for work unrelated to this project. Dr. Saag has received grants from Amgen, Eli Lilly, and Merck and has served as a paid consultant to Amgen, Eli Lilly, and Merck unrelated to this project.