Funding for this research was provided by:
Fondo Europeo de Desarrollo Regional and Fondo de Investigaciones Sanitarias. Instituto de Salud Carlos III. Ministerio de Economía y Competitividad. Gobierno de España (PI15/00164, PI15/00586, PI15/00566)
Received: 11 December 2018
Accepted: 28 May 2019
First Online: 20 June 2019
Ethics approval and consent to participate
: The study fulfils GPC standards and the principles of the latest version of the Helsinki Declaration (Brazil, 2013). The project has been approved by the Clinical Research Ethics Committee of Ramón y Cajal University Hospital in Madrid (ACTA 303), Nuestra Señora de Candelaria University Hospital in Santa Cruz de Tenerife (PI-18/16) and IDIAP Jordi Gol in Barcelona (C2748). In accordance with Spanish Law 15/1999 on personal data protection, confidentiality and anonymity is guaranteed. We obtained written informed consent from all participants.
: Not applicable.
: The authors declare that they have no competing interests.