Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection
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Hunn, Julia P.
Helms, J. Bernd
Howard, Jonathan C.
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (SFB680, SFB670)
German Academic Exchange Service (DE) (PhD scholarship)
International Graduate School for development, health and disease (PhD scholarship)