Funding for this research was provided by:
National Institute of Dental and Craniofacial Research (R03 DE019507-02, R01 DE027076, R56 DE13508)
National Cancer Institute (R37CA39681)
Received: 17 February 2019
Accepted: 13 November 2019
First Online: 13 December 2019
Ethics approval and consent to participate
: Human embryonic tissues were collected under guidelines approved by the Committee on Human Research at UCSF (BUA number: BU034548-04B), with patients’ written consent. The experiments and data collection had been performed in accordance with the Declarations of Helsinki. Mouse studies were approved by UCSF Institutional Animal Care and Use Committee (IACUC), accredited by Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC), with protocol number AN177146-02.
: The authors declare that they have no competing interests.